Connectivity Map

Connectivity Map. Economic Contribution The ultimate objective of biomedical research is to connect human diseases with the genes that underlie them and drugs that treat them We previously piloted the concept of a Connectivity Map (CMap), whereby genes, drugs, and disease states are connected by virtue of common gene-expression signatures

To build a Connectivity Map, the Broad brings together molecular biologists, genomics specialists, computational scientists, pharmacologists, chemists and chemical biologists, as well as expertise from across the breadth and depth of. 摘要：Connectivity Map 是药物基因组学研究领域的重要数据库，是 计算生物学 和药物筛选研究人员做研究时不得不重视的数据库。 它不仅提供大量宝贵的药物处理人类细胞系前后的基因表达谱数据，而且也提供了基于 模式匹配算法 的在线工具，用户提交合适的基因列表就能得到该数据库中与之相关.

Global Network Connection. World Map Point and Line Composition Concept

The Broad Institute's Connectivity Map is a collection of genome-wide, transcriptional expression data from cultured human cells The second challenge in the 2016 Connectivity Map series asked competitors to speed up the existing algorithm. The Research Article "The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease" (29 Sept

web mapping Examples of geovisualizations of global connectivity. The second challenge in the 2016 Connectivity Map series asked competitors to speed up the existing algorithm. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

Global network connection. World map point and line composition concept. The Connectivity Map is the most comprehensive effort yet for using genomics in a drug-discovery framework Here, we report more than a 1,000-fold scale-up of the CMap as part of the NIH LINCS Consortium, made possible by a new, low-cost, high-throughput reduced representation.